慢性痛には鎮痛薬が効かないのか

関節痛や炎症の痛みを和らげるための手段として、患者さまが一番に思いつくのは、やはり「鎮痛薬」ではないでしょうか。すでに使用している患者さまもおられると思いますが、「市販の痛み止めを使っても効かない」という声もよく聞きます。痛みを抑えるはずの鎮痛薬が効かないのはなぜか。それは、痛みのメカニズムと鎮痛薬の作用機序に関係があります。

2022.06.27 施術患者さまに伝えたい健康情報

痛みの発生メカニズム
 NSAIDsの作用機序
 アセトアミノフェンの作用機序
 鎮痛薬が慢性痛に効かない原因
 炎症以外の原因による痛みとは
 痛みは我慢せず、薬を上手く利用してもらう

※掲載情報につきましては、細心の注意をはらって掲載しておりますが、その内容を保証するものではありません。何卒ご了承ください。

痛みの発生メカニズム

組織が損傷を受けると、細胞膜にあるリン脂質はアラキドン酸を遊離し、シクロオキシゲナーゼ(COX)の作用によって、炎症メディエーターであるプロスタグランジン(PG)が生成されます。

このPGは、侵入した菌などが拡大しないように炎症反応を起こし、痛み、熱、腫れなどの症状を引き起こします。PG自体の発痛作用は弱いのですが、PGと同様に組織損傷の際に発生する発痛物質ブラジキニンの作用を増強させます。

これらの侵害刺激を、高閾値機械受容器またはポリモーダル受容器で受け取り、神経伝達路を上行し中枢に伝わることで、「痛み」が知覚されています。

【関連コラム】「痛み」を伝導するC線維の触覚機能＞＞

【関連コラム】身体を守る「炎症」と「免疫」の関係＞＞

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身体を守る「炎症」と「免疫」の関係

患者さまに伝えたい健康情報
胃の役割は、吸収ではなく消化【物販奮闘記】

患者さまに伝えたい健康情報
感情を左右する腸腸機能を左右する脳【物販奮闘記】

患者さまに伝えたい健康情報

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String <div class="layout_wrapper"> <div class="layout_left"> <div class="layout_left_inner"> <div class="main_wrapper"> <h1 class="main_title">慢性痛には鎮痛薬が効かないのか</h1> <p class="main_doc">関節痛や炎症の痛みを和らげるための手段として、患者さまが一番に思いつくのは、やはり「鎮痛薬」ではないでしょうか。すでに使用している患者さまもおられると思いますが、「市販の痛み止めを使っても効かない」という声もよく聞きます。痛みを抑えるはずの鎮痛薬が効かないのはなぜか。それは、痛みのメカニズムと鎮痛薬の作用機序に関係があります。</p> <div class="main_info_wrapper"> <span class="main_column_date">2022.06.27</span> <a href="https://honetsugi-academy-test.azurewebsites.net/community/ch-8c1zb/" class="main_column_category type_channel">施術</a> <a href="https://honetsugi-academy-test.azurewebsites.net/column/catemb1zb/" class="main_column_category type_category">患者さまに伝えたい健康情報</a> </div> <div class="top_sns_link_list_wrapper"> <ul class="sns_link_list"> <li class="sns_link_list_item"> <a href="http://twitter.com/share?url=https://honetsugi-academy-test.azurewebsites.net/column/catemb1zb/notefo1zb.php&text=慢性痛には鎮痛薬が効かないのか：アトラアカデミー" target="_blank" rel="noopener"><img src="/img/icon/icon_tw.png"></a> </li> <li class="sns_link_list_item"> <a href="http://line.me/R/msg/text/?慢性痛には鎮痛薬が効かないのか：アトラアカデミー https://honetsugi-academy-test.azurewebsites.net/column/catemb1zb/notefo1zb.php" target="_blank" rel="noopener"><img src="/img/icon/icon_li.png"></a> </li> <li class="sns_link_list_item"> <a href="https://www.facebook.com/sharer/sharer.php?u=https://honetsugi-academy-test.azurewebsites.net/column/catemb1zb/notefo1zb.php" target="_blank" rel="noopener"><span><img src="/img/icon/icon_fb.png"></a> </li> </ul> </div> </div> <div class="main_section_wrapper"> <div class="main_section_container"> <h2 class="main_section_title">目次</h2> <div class="main_section_doc_wrapper"> <p class="main_section_doc"><a href="#point1">痛みの発生メカニズム</a><br><a href="#point2">NSAIDsの作用機序</a><br><a href="#point3">アセトアミノフェンの作用機序</a><br><a href="#point4">鎮痛薬が慢性痛に効かない原因</a><br><a href="#point5">炎症以外の原因による痛みとは</a><br><a href="#point6">痛みは我慢せず、薬を上手く利用してもらう</a><br><br><br><span style="font-size:12px;">※掲載情報につきましては、細心の注意をはらって掲載しておりますが、その内容を保証するものではありません。何卒ご了承ください。</span> <div id="point1"></div> </p> </div> </div> <div class="main_section_container"> <h2 class="main_section_title">痛みの発生メカニズム</h2> <div class="main_section_doc_wrapper"> <p class="main_section_doc">組織が損傷を受けると、細胞膜にあるリン脂質はアラキドン酸を遊離し、シクロオキシゲナーゼ(COX)の作用によって、炎症メディエーターであるプロスタグランジン(PG)が生成されます。<br><br>このPGは、侵入した菌などが拡大しないように炎症反応を起こし、痛み、熱、腫れなどの症状を引き起こします。PG自体の発痛作用は弱いのですが、PGと同様に組織損傷の際に発生する発痛物質ブラジキニンの作用を増強させます。<br><br>これらの侵害刺激を、高閾値機械受容器またはポリモーダル受容器で受け取り、神経伝達路を上行し中枢に伝わることで、「痛み」が知覚されています。<br><br><br><a href="https://www.hone-u.com/column/cate0b1zb/note5k1zb.php?from=notefo1zb">【関連コラム】「痛み」を伝導するC線維の触覚機能＞＞</a><br><br><a href="https://www.hone-u.com/column/catemb1zb/note5o1zb.php?from=notefo1zb">【関連コラム】身体を守る「炎症」と「免疫」の関係＞＞</a> <div id="point2"></div> </p> </div> </div> </div> <div class="limited_section_wrapper"> <div class="limited_section_inner"> <div class="limited_section_title">この記事は<span>会員限定</span>です。<br 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</div> <div class="layout_list_box type_mailmgz"> <div class="right_mailmgz_arapper"> <div class="download_cnts_wrapper"> <div class="download_cnts_img"><img src="https://honetsugiacademy.blob.core.windows.net/temp-honetsugi-academy-image/push_download/thumb/74a69a16bb0e4e7_0x200.png" alt="事業計画書の書き方" loading="lazy"></div> <div class="download_cnts_title"><span>無料DL</span>事業計画書の書き方</div> <p class="download_cnts_doc">接骨院を開業する際に必要な事業計画書は...</p> <div class="page_common_btn"><a href="/tool/document/det9h1zb.php" class="type_small hovimg">無料ダウンロード</a></div> </div> <div class="mailmgz_btn"><a href="https://honetsugi-academy-test.azurewebsites.net/user/new_frm.php?ref=aHR0cHM6Ly9ob25ldHN1ZmL0NXZ01SetVGZhNWYtk2F6dXJld2Vic2l0ZXMubmVxIWblRXYj9ibtVHbvN2L0emIvbm90ZWZvMXpiLnBocA||" class="hovimg">メルマガ会員登録はこちら</a></div> </div> </div> </div> </div> <div class="layout_left"> <div class="connection_wrapper PC_ONLY"> <h3 class="cc_title">関連記事</h3> <ul class="cc_list"> <li class="cc_list_item"> <a href="https://honetsugi-academy-test.azurewebsites.net/column/catemb1zb/note5o1zb.php" class="cc_list_item_inner"> <div class="cc_list_item_img_wrapper"><img src="https://honetsugiacademy.blob.core.windows.net/temp-honetsugi-academy-image/" alt="接骨院で安定した自費売上を作り続けるには" loading="lazy"></div> <div class="cc_list_item_date">2022.03.28</div> <div class="cc_list_item_title">身体を守る「炎症」と「免疫」の関係</div> <div class="cc_list_item_doc">身体が痛みを感じる要因の一つとして、患部の「炎症」が挙げられます。「炎症」という言葉はよく知られており、赤く腫れたり熱を持ったりする症状であることは多くの人が理解しているでしょう。しかし、誰もが聞いたことのある言葉でも、「炎症」を起こす生体防御反応の仕組みを正しく理解している人は少ないのではないでしょうか。患者の健康を守る職業に従事している者として、広義で「炎症」というものを考えてみましょう。</div> </a> </li> <li class="cc_list_item"> <a href="https://honetsugi-academy-test.azurewebsites.net/column/catemb1zb/note1j1zb.php" class="cc_list_item_inner"> <div class="cc_list_item_img_wrapper"><img src="https://honetsugiacademy.blob.core.windows.net/temp-honetsugi-academy-image/" alt="接骨院で安定した自費売上を作り続けるには" loading="lazy"></div> <div class="cc_list_item_date">2022.09.16</div> <div class="cc_list_item_title">胃の役割は、吸収ではなく消化【物販奮闘記】</div> <div class="cc_list_item_doc">前回の続きで、胃の解剖学・生理学のお話です。食道から繋がっている胃の入口部分を噴門、胃から十二指腸へと続く出口部分を幽門といいます。胃壁は、内側から粘膜、３つの筋層、一番外側の腹膜で覆われています。胃粘膜にはヒダが形成されているので、伸びたり縮んだりすることができます。食べ物が胃の中に入ると、ひだが伸びて最大約３倍に膨らみます。今回は「胃液の分泌」について解説していきます。</div> </a> </li> <li class="cc_list_item"> <a href="https://honetsugi-academy-test.azurewebsites.net/column/catemb1zb/notesd1zb.php" class="cc_list_item_inner"> <div class="cc_list_item_img_wrapper"><img src="https://honetsugiacademy.blob.core.windows.net/temp-honetsugi-academy-image/" alt="接骨院で安定した自費売上を作り続けるには" loading="lazy"></div> <div class="cc_list_item_date">2022.09.30</div> <div class="cc_list_item_title">感情を左右する腸腸機能を左右する脳【物販奮闘記】</div> <div class="cc_list_item_doc">特別に勉強をした方ではない限り、「腸」は身体にとって不要なものを便をとして排泄してくれる、くらいの認識しかありません。今回は、腸の神秘的な役割をお伝えしたいと思います。</div> </a> </li> </ul> </div> <div class="page_common_btn type_category layout_left_inner"> <a href="https://honetsugi-academy-test.azurewebsites.net/column/" class="type_double hovimg">記事一覧にもどる</a> <a href="https://honetsugi-academy-test.azurewebsites.net/" class="type_double hovimg">トップページにもどる</a> </div> <div class="layout_left_inner"> <div class="login_info_wrapper"> <div class="login_info_box"> <div class="login_info_box_header"> <div class="box_header_logo"><img src="/img/logo.svg" alt="アトラアカデミー" loading="lazy"></div> <div class="box_header_cnt">会員数<span>9,003</span>人</div> </div> <div class="login_info_box_benefits"> <div class="benefits_header"><span class="PC_I">アトラアカデミーに</span>無料会員登録すると</div> <ul class="benefits_list"> <li> <div class="benefits_list_img"><img src="/column/img/icon_speaker.png" alt="" loading="lazy"></div> <div class="benefits_list_doc">法令など業界の<brPC class="PC_I">最新情報をGet！</div> </li> <li> <div class="benefits_list_img"><img src="/column/img/icon_movie.png" alt="" loading="lazy"></div> <div class="benefits_list_doc">オリジナル動画が<br class="PC_I">見放題</div> </li> <li> <div class="benefits_list_img"><img src="/column/img/icon_note.png" alt="" loading="lazy"></div> <div class="benefits_list_doc">実務に役立つ資料を<br class="PC_I">ダウンロード</div> </li> </ul> </div> </div> </div> </div> <div class="register_btn_wrapper layout_left_inner"> <div class="register_btn"><a href="https://honetsugi-academy-test.azurewebsites.net/user/new_frm.php?ref=aHR0cHM6Ly9ob25ldHN1ZmL0NXZ01SetVGZhNWYtk2F6dXJld2Vic2l0ZXMubmVxIWblRXYj9ibtVHbvN2L0emIvbm90ZWZvMXpiLnBocA||" class="hovimg">無料会員登録はこちら</a></div> <div class="register_text"><a href="https://honetsugi-academy-test.azurewebsites.net/login_frm.php?ref=aHR0cHM6Ly9ob25ldHN1ZmL0NXZ01SetVGZhNWYtk2F6dXJld2Vic2l0ZXMubmVxIWblRXYj9ibtVHbvN2L0emIvbm90ZWZvMXpiLnBocA||">すでに会員の方はこちら</a></div> </div> </div> </div> <input type="hidden" name="ak" id="f-ak" value="fo1zb">

myjs

String/column/cate/js/note.js

【$User】/C:/home/site/wwwroot/lib/inc/default.tpl - line 63

Object [9]
pk_user	String
sess_key	Stringnet_azurewebsites_honetsugi-academy-test
cookie_key	Stringnet_azurewebsites_honetsugi-academy-test_pk
cookie_hash	Stringnet_azurewebsites_honetsugi-academy-test_hash
us_hash	String
key	Stringpk_user
loginflg	Booleanfalse
cookie_loginflg	Booleanfalse
just_login	Booleanfalse

【$Client】/C:/home/site/wwwroot/lib/inc/default.tpl - line 63

Object [8]
agent	StringMozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)
ip	String3.133.136.214
media	Stringpc
userset_media	String
media_type	Null
browser	Stringunknown
carrier	Null
robot	Booleanfalse

【$_SERVER】/C:/home/site/wwwroot/lib/inc/default.tpl - line 63

Array [193]
_FCGI_X_PIPE_	String\\.\pipe\IISFCGI-ff5fe286-a144-4968-be56-7c87b416208a
PHP_FCGI_MAX_REQUESTS	String10000
PHPRC	StringC:\local\Config\PHP-5.6.40\php.ini
APPSETTING_COMMAND	StringC:\home\SiteExtensions\ComposerExtension\Hooks\deploy.cmd
APP_POOL_CONFIG	StringD:\DWASFiles\Sites\honetsugi-academy__410c\Config\applicationhost.config
APP_POOL_ID	Stringhonetsugi-academy__410c
COMPOSER_ARGS	String--prefer-dist --no-dev --optimize-autoloader
PROCESSOR_ARCHITEW6432	StringAMD64
SystemDrive	StringC:
ProgramFiles(x86)	StringC:\Program Files (x86)
ProgramW6432	StringC:\Program Files
PROCESSOR_IDENTIFIER	StringIntel64 Family 6 Model 85 Stepping 7, GenuineIntel
DOTNET_HOSTING_OPTIMIZATION_CACHE	StringC:\DotNetCache
PROCESSOR_ARCHITECTURE	Stringx86
DriverData	StringC:\Windows\System32\Drivers\DriverData
Path	StringC:\Python27;C:\Program Files (x86)\PHP\v5.6;C:\Program Files (x86)\nodejs\6.9.1;C:\Windows\system32;C:\Windows;C:\Windows\System32\Wbem;C:\Windows\System32\WindowsPowerShell\v1.0\;C:\Windows\System32\OpenSSH\;C:\Program Files\Microsoft Network Monitor 3\;C:\Users\packer\AppData\Roaming\npm;C:\Program Files (x86)\nodejs\;C:\Program Files (x86)\Mercurial\;C:\Program Files\Git\cmd;C:\Program Files (x86)\Microsoft ASP.NET\ASP.NET Web Pages\v1.0\;C:\Program Files (x86)\dotnet;C:\Program Files\dotnet;C:\Windows\system32\config\systemprofile\AppData\Local\Microsoft\WindowsApps;C:\Program Files\Java\Adoptium-Eclipse-Temurin-OpenJDK-8u392\bin;;C:\home\SiteExtensions\ComposerExtension\Commands;C:\local\AppData\Composer\vendor\bin
AZURE_TOMCAT7_CMDLINE	String-Dport.http=%HTTP_PLATFORM_PORT% -Djava.util.logging.config.file="C:\Program Files (x86)\apache-tomcat-7.0.94\conf\logging.properties" -Djava.util.logging.manager=org.apache.juli.ClassLoaderLogManager -Dsite.logdir="d:/home/LogFiles/" -Dsite.tempdir="d:\home\site\workdir" -classpath "C:\Program Files (x86)\apache-tomcat-7.0.94\bin\bootstrap.jar;C:\Program Files (x86)\apache-tomcat-7.0.94\bin\tomcat-juli.jar" -Dcatalina.base="C:\Program Files (x86)\apache-tomcat-7.0.94" -Djava.io.tmpdir="d:\home\site\workdir" org.apache.catalina.startup.Bootstrap
AZURE_JETTY9_HOME	StringC:\Program Files (x86)\jetty-distribution-9.1.0.v20131115
AZURE_TOMCAT85_CMDLINE	String-noverify -Djava.net.preferIPv4Stack=true -Dcatalina.instance.name=%WEBSITE_INSTANCE_ID% -Dport.http=%HTTP_PLATFORM_PORT% -Djava.util.logging.config.file="C:\Program Files (x86)\apache-tomcat-8.5.96\conf\logging.properties" -Djava.util.logging.manager=org.apache.juli.ClassLoaderLogManager -Dsite.logdir="d:/home/LogFiles/" -Dsite.tempdir="d:\home\site\workdir" -classpath "C:\Program Files (x86)\apache-tomcat-8.5.96\bin\bootstrap.jar;C:\Program Files (x86)\apache-tomcat-8.5.96\bin\tomcat-juli.jar" -Dcatalina.base="C:\Program Files (x86)\apache-tomcat-8.5.96" -Djava.io.tmpdir="d:\home\site\workdir" org.apache.catalina.startup.Bootstrap
AZURE_TOMCAT90_HOME	StringC:\Program Files\apache-tomcat-9.0.83
PROCESSOR_REVISION	String5507
TEMP	StringC:\local\Temp
USERPROFILE	StringC:\local\UserProfile
USERNAME	Stringdw1ldwk0000HT$
SystemRoot	StringC:\Windows
AZURE_TOMCAT85_HOME	StringC:\Program Files\apache-tomcat-8.5.96
AZURE_TOMCAT7_HOME	StringC:\Program Files (x86)\apache-tomcat-7.0.94
AZURE_JETTY9_CMDLINE	String-Djava.net.preferIPv4Stack=true -Djetty.port=%HTTP_PLATFORM_PORT% -Djetty.base="D:\Program Files (x86)\jetty-distribution-9.1.0.v20131115" -Djetty.webapps="d:\home\site\wwwroot\webapps" -jar "D:\Program Files (x86)\jetty-distribution-9.1.0.v20131115\start.jar" etc\jetty-logging.xml
CommonProgramFiles	StringC:\Program Files (x86)\Common Files
ProgramData	StringC:\local\ProgramData
AZURE_JETTY93_HOME	StringC:\Program Files (x86)\jetty-distribution-9.3.25.v20180904
COMPUTERNAME	Stringdw1ldwk0000HT
RoleName	Stringdw1LargeDedicatedWebWorkerRole
AZURE_TOMCAT10_HOME	StringC:\Program Files\apache-tomcat-10.1.16
CommonProgramW6432	StringC:\Program Files\Common Files
RoleInstanceId	Stringdw1LargeDedicatedWebWorkerRole_641
AZURE_TOMCAT90_CMDLINE	String-noverify -Djava.net.preferIPv4Stack=true -Dcatalina.instance.name=%WEBSITE_INSTANCE_ID% -Dport.http=%HTTP_PLATFORM_PORT% -Djava.util.logging.config.file="C:\Program Files (x86)\apache-tomcat-9.0.83\conf\logging.properties" -Djava.util.logging.manager=org.apache.juli.ClassLoaderLogManager -Dsite.logdir="d:/home/LogFiles/" -Dsite.tempdir="d:\home\site\workdir" -classpath "C:\Program Files (x86)\apache-tomcat-9.0.83\bin\bootstrap.jar;C:\Program Files (x86)\apache-tomcat-9.0.83\bin\tomcat-juli.jar" -Dcatalina.base="C:\Program Files (x86)\apache-tomcat-9.0.83" -Djava.io.tmpdir="d:\home\site\workdir" org.apache.catalina.startup.Bootstrap
TMP	StringC:\local\Temp
RoleRoot	StringE:
AZURE_JETTY93_CMDLINE	String-Djava.net.preferIPv4Stack=true -Djetty.port=%HTTP_PLATFORM_PORT% -Djetty.base="D:\Program Files (x86)\jetty-distribution-9.3.25.v20180904" -Djetty.webapps="d:\home\site\wwwroot\webapps" -jar "D:\Program Files (x86)\jetty-distribution-9.3.25.v20180904\start.jar" etc\jetty-logging.xml
CommonProgramFiles(x86)	StringC:\Program Files (x86)\Common Files
AZURE_TOMCAT10_CMDLINE	String-noverify -Djava.net.preferIPv4Stack=true -Dcatalina.instance.name=%WEBSITE_INSTANCE_ID% -Dport.http=%HTTP_PLATFORM_PORT% -Djava.util.logging.config.file="C:\Program Files\apache-tomcat-10.1.16\conf\logging.properties" -Djava.util.logging.manager=org.apache.juli.ClassLoaderLogManager -Dsite.logdir="d:/home/LogFiles/" -Dsite.tempdir="d:\home\site\workdir" -classpath "C:\Program Files\apache-tomcat-10.1.16\bin\bootstrap.jar;C:\Program Files\apache-tomcat-10.1.16\bin\tomcat-juli.jar" -Dcatalina.base="C:\Program Files\apache-tomcat-10.1.16" -Djava.io.tmpdir="d:\home\site\workdir" org.apache.catalina.startup.Bootstrap
WEBSITE_CONFIGURATION_READY	String1
windir	StringC:\Windows
NUMBER_OF_PROCESSORS	String4
OS	StringWindows_NT
ProgramFiles	StringC:\Program Files (x86)
ComSpec	StringC:\Windows\system32\cmd.exe
PATHEXT	String.COM;.EXE;.BAT;.CMD;.VBS;.VBE;.JS;.JSE;.WSF;.WSH;.MSC;.CPL;.PY;.PYW
AZURE_TOMCAT8_CMDLINE	String-Dport.http=%HTTP_PLATFORM_PORT% -Djava.util.logging.config.file="C:\Program Files (x86)\apache-tomcat-8.0.53\conf\logging.properties" -Djava.util.logging.manager=org.apache.juli.ClassLoaderLogManager -Dsite.logdir="d:/home/LogFiles/" -Dsite.tempdir="d:\home\site\workdir" -classpath "C:\Program Files (x86)\apache-tomcat-8.0.53\bin\bootstrap.jar;C:\Program Files (x86)\apache-tomcat-8.0.53\bin\tomcat-juli.jar" -Dcatalina.base="C:\Program Files (x86)\apache-tomcat-8.0.53" -Djava.io.tmpdir="d:\home\site\workdir" org.apache.catalina.startup.Bootstrap
ALLUSERSPROFILE	StringC:\local\ProgramData
PSModulePath	StringC:\Program Files\WindowsPowerShell\Modules;C:\Windows\system32\WindowsPowerShell\v1.0\Modules;C:\Program Files\WindowsPowerShell\Modules\;C:\Program Files (x86)\Microsoft SDKs\Azure\PowerShell\ResourceManager\AzureResourceManager\;C:\Program Files (x86)\Microsoft SDKs\Azure\PowerShell\ServiceManagement\;C:\Program Files (x86)\Microsoft SDKs\Azure\PowerShell\Storage\
APPDATA	StringC:\local\AppData
USERDOMAIN	StringWORKGROUP
PROCESSOR_LEVEL	String6
LOCALAPPDATA	StringC:\local\LocalAppData
ResourceDrive	StringD:\
MonAgentClientLocation	StringC:\Packages\Plugins\Microsoft.Azure.Geneva.GenevaMonitoring\2.45.0.11\Monitoring\Agent
AZURE_TOMCAT8_HOME	StringC:\Program Files (x86)\apache-tomcat-8.0.53
PUBLIC	StringC:\Users\Public
WEBSITE_NODE_DEFAULT_VERSION	String6.9.1
APPSETTING_WEBSITE_NODE_DEFAULT_VERSION	String6.9.1
ScmType	StringNone
APPSETTING_ScmType	StringNone
WEBSITE_SITE_NAME	Stringhonetsugi-academy
APPSETTING_WEBSITE_SITE_NAME	Stringhonetsugi-academy
WEBSITE_AUTH_ENABLED	StringFalse
APPSETTING_WEBSITE_AUTH_ENABLED	StringFalse
REMOTEDEBUGGINGVERSION	String11.0.611103.400
APPSETTING_REMOTEDEBUGGINGVERSION	String11.0.611103.400
FUNCTIONS_RUNTIME_SCALE_MONITORING_ENABLED	String0
APPSETTING_FUNCTIONS_RUNTIME_SCALE_MONITORING_ENABLED	String0
WEBSITE_AUTH_LOGOUT_PATH	String/.auth/logout
APPSETTING_WEBSITE_AUTH_LOGOUT_PATH	String/.auth/logout
WEBSITE_AUTH_AUTO_AAD	StringFalse
APPSETTING_WEBSITE_AUTH_AUTO_AAD	StringFalse
AZUREFILESSTORAGE_dev-logs	Stringhonetsugiacademy\|dev-logs\|08wWW1e0ltvN/HtNJjCM7suKKArWYqY4F5LqxQp0i8Ah+sbBN+626p71BeuCHrLwkPEytw/SHIzz5YBBTyAFRA==\|/mounts/dev-logs\|
REGION_NAME	StringJapan West
HOME	StringC:\home
HOME_EXPANDED	StringD:\DWASFiles\Sites\honetsugi-academy__410c\VirtualDirectory0
LOCAL_EXPANDED	StringD:\DWASFiles\Sites\honetsugi-academy__410c
windows_tracing_flags	String
windows_tracing_logfile	String
WEBSITE_INSTANCE_ID	String2eafb6dc94224bdf7ab3c077830c7fcd177dea0ad485db0be0f02ffcbdb4d2ba
WEBSITE_HTTPLOGGING_ENABLED	String0
WEBSITE_SCM_ALWAYS_ON_ENABLED	String0
WEBSITE_ISOLATION	Stringpico
WEBSITE_OS	Stringwindows
WEBSITE_DEPLOYMENT_ID	Stringhonetsugi-academy__410c
WEBSITE_INFRASTRUCTURE_IP	String172.19.64.13
WEBSITE_COMPUTE_MODE	StringDedicated
WEBSITE_SKU	StringStandard
WEBSITE_ELASTIC_SCALING_ENABLED	String0
WEBSITE_SCM_SEPARATE_STATUS	String1
WEBSITE_IIS_SITE_NAME	Stringhonetsugi-academy__410c
WEBSITE_APPSERVICEAPPLOGS_TRACE_ENABLED	Stringtrue
WEBSITE_CHANGEANALYSISSCAN_ENABLED	String1
MicrosoftInstrumentationEngine_LatestPath	StringC:\Program Files (x86)\SiteExtensions\InstrumentationEngine\1.0.43
JAVA_HOME	StringC:\Program Files\Java\Adoptium-Eclipse-Temurin-OpenJDK-8u392
SITE_BITNESS	Stringx86
WEBSITE_AUTH_ENCRYPTION_KEY	String3FFD5C259672EEA402334F30B547576FDFD5DEF0A72C6EE630A1066CD3BF8200
WEBSITE_AUTH_SIGNING_KEY	String42E3BA98940DEBBD9B7EE16C04CBBCC5901058AC9AEA52D4F32568FE920060EB
WEBSITE_PROACTIVE_AUTOHEAL_ENABLED	StringTrue
WEBSITE_PROACTIVE_STACKTRACING_ENABLED	StringTrue
WEBSITE_PROACTIVE_CRASHMONITORING_ENABLED	StringTrue
WEBSITE_CRASHMONITORING_USE_DEBUGDIAG	StringTrue
WEBSITE_DYNAMIC_CACHE	String1
WEBSITE_FRAMEWORK_JIT	String1
WEBSITE_HOME_STAMPNAME	Stringwaws-prod-os1-001
WEBSITE_CURRENT_STAMPNAME	Stringwaws-prod-os1-001
WEBSOCKET_CONCURRENT_REQUEST_LIMIT	String-1
WEBSITE_VOLUME_TYPE	StringPrimaryStorageVolume
WEBSITE_OWNER_NAME	Stringf15746fc-4d45-421a-a228-9ff5fd9a7333+JapanWestwebspace
WEBSITE_RESOURCE_GROUP	Stringhonetsugi-academy
WEBSITE_CONTAINER_READY	String1
WEBSITE_MOUNT_dev-logs	StringC:\mounts\dev-logs
WEBSITE_PHYSICAL_MEMORY_MB	String8140
WEBSITE_JAVA_MAX_HEAP_MB	String5698
WEBSITE_PLATFORM_VERSION	String103.0.7.210
REMOTEDEBUGGINGPORT	String
REMOTEDEBUGGINGBITVERSION	Stringvx86
WEBSITE_LOCALCACHE_ENABLED	StringFalse
WEBSITE_HOSTNAME	Stringhonetsugi-academy-test.azurewebsites.net
WEBSITE_RELAYS	String
WEBSITE_REWRITE_TABLE	String
WEBSITE_DAAS_EXTENSIONPATH	StringC:\Program Files (x86)\SiteExtensions\DaaS\4.6.24926.1
ORIG_PATH_INFO	String/module/quarter.php
URL	String/module/quarter.php
SERVER_SOFTWARE	StringMicrosoft-IIS/10.0
SERVER_PROTOCOL	StringHTTP/1.1
SERVER_PORT_SECURE	String1
SERVER_PORT	String443
SERVER_NAME	Stringhonetsugi-academy-test.azurewebsites.net
SCRIPT_NAME	String/module/quarter.php
SCRIPT_FILENAME	StringC:\home\site\wwwroot\module\quarter.php
REQUEST_URI	String/column/catemb1zb/notefo1zb.php
REQUEST_METHOD	StringGET
REMOTE_USER	String
REMOTE_PORT	String5658
REMOTE_HOST	String3.133.136.214
REMOTE_ADDR	String3.133.136.214
QUERY_STRING	Stringqu=/column/cate/note.php&ck=mb1zb&ak=fo1zb
PATH_TRANSLATED	StringC:\home\site\wwwroot\module\quarter.php
LOGON_USER	String
LOCAL_ADDR	String172.19.64.13
INSTANCE_META_PATH	String/LM/W3SVC/889941130
INSTANCE_NAME	StringHONETSUGI-ACADEMY__410C
INSTANCE_ID	String889941130
HTTPS_SERVER_SUBJECT	StringCN=*.azurewebsites.net, O=Microsoft Corporation, L=Redmond, S=WA, C=US
HTTPS_SERVER_ISSUER	StringCN=Microsoft Azure RSA TLS Issuing CA 04, O=Microsoft Corporation, C=US
HTTPS_SECRETKEYSIZE	String2048
HTTPS_KEYSIZE	String256
HTTPS	Stringon
GATEWAY_INTERFACE	StringCGI/1.1
DOCUMENT_ROOT	StringC:\home\site\wwwroot
CONTENT_TYPE	String
CONTENT_LENGTH	String0
CERT_SUBJECT	String
CERT_SERIALNUMBER	String
CERT_ISSUER	String
CERT_FLAGS	String
CERT_COOKIE	String
AUTH_USER	String
AUTH_PASSWORD	String
AUTH_TYPE	String
APPL_PHYSICAL_PATH	StringC:\home\site\wwwroot\
APPL_MD_PATH	String/LM/W3SVC/889941130/ROOT
IIS_UrlRewriteModule	String7,1,1993,2336
LOG_QUERY_STRING	Stringqu=/column/cate/note.php&ck=mb1zb&ak=fo1zb&X-ARR-LOG-ID=98b7f890-ba15-48d0-9f77-a17ba5b62af2
UNENCODED_URL	String/column/catemb1zb/notefo1zb.php
IIS_WasUrlRewritten	String1
HTTP_X_WAWS_UNENCODED_URL	String/column/catemb1zb/notefo1zb.php
HTTP_X_ORIGINAL_URL	String/column/catemb1zb/notefo1zb.php
HTTP_X_FORWARDED_FOR	String3.133.136.214:5658
HTTP_X_FORWARDED_TLSVERSION	String1.3
HTTP_X_ARR_SSL	String2048\|256\|CN=Microsoft Azure RSA TLS Issuing CA 04, O=Microsoft Corporation, C=US\|CN=*.azurewebsites.net, O=Microsoft Corporation, L=Redmond, S=WA, C=US
HTTP_X_APPSERVICE_PROTO	Stringhttps
HTTP_X_FORWARDED_PROTO	Stringhttps
HTTP_WAS_DEFAULT_HOSTNAME	Stringhonetsugi-academy-test.azurewebsites.net
HTTP_X_SITE_DEPLOYMENT_ID	Stringhonetsugi-academy__410c
HTTP_DISGUISED_HOST	Stringhonetsugi-academy-test.azurewebsites.net
HTTP_CLIENT_IP	String3.133.136.214:5658
HTTP_X_ARR_LOG_ID	String98b7f890-ba15-48d0-9f77-a17ba5b62af2
HTTP_USER_AGENT	StringMozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)
HTTP_MAX_FORWARDS	String10
HTTP_HOST	Stringhonetsugi-academy-test.azurewebsites.net
HTTP_ACCEPT_ENCODING	Stringgzip, br, zstd, deflate
HTTP_ACCEPT	String/
HTTP_CONTENT_LENGTH	String0
FCGI_ROLE	StringRESPONDER
PHP_SELF	String/module/quarter.php
REQUEST_TIME_FLOAT	Double1733249248.3335
REQUEST_TIME	Integer1733249248

【実行したSQL】/C:/home/site/wwwroot/lib/inc/default.tpl - line 63

Array [37]

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00157090
query	Stringselect * from t500_article where akey = :akey: and status = 1

Array [3]
file	String/column\lib\classes\ArticleDetail.class - line 48
time	String0.00198100
query	Stringselect * from t502_section where akey = :akey: order by sort

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00164600
query	Stringselect * from t730_items where ikey = :ikey: and view_flg = 1 and (fdate is null or fdate <= :cdate:) and (tdate is null or tdate >= :cdate:)

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00167800
query	Stringselect * from t500_article where akey = :akey: and status = 1

Array [3]
file	String/column\lib\classes\ArticleNearList.class - line 53
time	String0.00204800
query	Stringselect * from t500_article where ckey = :ckey: and status = 1 and chkey in (select chkey from t200_channel where status = 1) order by adate desc, akey desc

Array [3]
file	String/admin\member\article\category\lib\classes\CategoryName.class - line 28
time	String0.00156210
query	Stringselect ckey, cname from t510_category order by sort, ckey desc

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00165100
query	Stringselect * from t500_article where akey = :akey:

Array [3]
file	StringC:\home\site\wwwroot\seminar\lib\classes\SeminarListCore.class - line 139
time	String0.00166800
query	Stringselect * from t300_normal as t300 where t300.status = 1 and chkey in (select chkey from t200_channel where status = 1) order by t300.snkey

Array [3]
file	StringC:\home\site\wwwroot\seminar\lib\classes\SeminarListCore.class - line 149
time	String0.00220300
query	Stringselect * from t310_lesson as t310 where t310.status in (1, 2, 3) and ((t310.tdate is null and t310.ldate > :ldate:) or t310.tdate >= :tdate:) order by t310.lkey, t310.ldate, t310.ftime

Array [3]
file	String/column\lib\classes\ArticleList.class - line 80
time	String0.00251510
query	Stringselect t500., t510.cname, t502. from t500_article as t500 join t510_category as t510 on (t500.ckey = t510.ckey) join ( SELECT t502.akey, simg_dir, simg FROM t502_section as t502 INNER JOIN ( SELECT akey, MIN(skey) AS min FROM t502_section GROUP BY akey ) AS t502_min ON t502.skey = t502_min.min AND t502.akey = t502_min.akey ) as t502 on (t500.akey = t502.akey) where 1 = 1 and status = 1 and t510.chkey in (select chkey from t200_channel where status = 1) and t500.ckey not in (3, 4) and t510.ckey = :ckey: order by t500.adate desc, t500.akey desc limit 12 offset 0

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00219700
query	Stringselect count(t500.akey) as cnt from t500_article as t500 join t510_category as t510 on (t500.ckey = t510.ckey) join ( SELECT t502.akey, simg_dir, simg FROM t502_section as t502 INNER JOIN ( SELECT akey, MIN(skey) AS min FROM t502_section GROUP BY akey ) AS t502_min ON t502.skey = t502_min.min AND t502.akey = t502_min.akey ) as t502 on (t500.akey = t502.akey) where 1 = 1 and status = 1 and t510.chkey in (select chkey from t200_channel where status = 1) and t500.ckey not in (3, 4) and t510.ckey = :ckey:

Array [3]
file	String/column\lib\classes\ArticleCategoryList.class - line 66
time	String0.00188210
query	Stringselect * from t500_article where status = 1 and ckey not in(4)

Array [3]
file	String/column\lib\classes\ArticleCategoryList.class - line 36
time	String0.00287010
query	Stringselect * from t510_category where 1 = 1 and list_flg = 1 and ckey = :ckey1: or ckey = :ckey2: or ckey = :ckey3: or ckey = :ckey4: or ckey = :ckey5: or ckey = :ckey6: or ckey = :ckey7: or ckey = :ckey8: or ckey = :ckey9: or ckey = :ckey10: or ckey = :ckey11: or ckey = :ckey12: and chkey in (select chkey from t200_channel where status = 1) order by sort asc

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00157500
query	Stringselect * from t200_channel where chkey = :chkey:

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00151400
query	Stringselect count(chkey) as cnt from t220_channel_follower where chkey = :chkey:

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00153900
query	Stringselect * from t510_category where ckey = :ckey:

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00167490
query	Stringselect count(akey) as cnt from t500_article where ckey = :ckey: and status = 1

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00224900
query	Stringselect count(pk_user) as cnt from t100_user

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00215100
query	Stringselect count(pk_taikai) as cnt from t109_taikai

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00197980
query	Stringselect * from t512_article_banner where (fdate is null or fdate <= :fdate:) and (tdate is null or tdate >= :tdate:) order by abkey desc

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00160600
query	Stringselect t620.* from t513_article_download as t513 join t620_download as t620 on (t513.dkey = t620.dkey) where (t513.fdate is null or t513.fdate <= :fdate:) and (t513.tdate is null or t513.tdate >= :tdate:) and t620.category = 50 order by t513.adkey desc

Array [3]
file	String/column\cate\lib\classes\PushSeminarList.class - line 65
time	String0.00164100
query	Stringselect * from t514_article_seminar where (fdate is null or fdate <= :fdate:) and (tdate is null or tdate >= :tdate:) order by askey desc

Array [3]
file	String/column\cate\lib\classes\PushSeminarList.class - line 92
time	String0.00418590
query	Stringselect * from t300_normal where ( seminar_type = 30 or (seminar_type = 10 and snkey in ( select snkey from t310_lesson where (tdate is not null and tdate >= :seminar_tdate:) or (tdate is null and ldate >= :ldate:) ) ) )

Array [3]
file	String/seminar\practice\lib\classes\LimitedLessonList.class - line 67
time	String0.00178890
query	Stringselect * from t430_lesson as t430 join t420_group as t420 on (t430.slkey = t420.slkey and t430.gkey = t420.gkey) and t420.view_flg = 1 and ((t420.tdate is null and t430.ldate > :ldate:) or (t420.tdate >= :tdate: and t430.ldate >= :ldate:)) order by t430.slkey, t430.ldate, t430.ftime

Array [3]
file	String/seminar\practice\lib\classes\LimitedLessonList.class - line 137
time	String0.00160720
query	Stringselect * from t400_limited where chkey in (select chkey from t200_channel where status = 1) and status <> 9 and view_flg = 1 and status <> 3 and ( slkey = :slkey1:) order by slkey desc

Array [3]
file	String/seminar\practice\lib\classes\LimitedLessonList.class - line 139
time	String0.00150800
query	Stringselect * from t400_limited where chkey in (select chkey from t200_channel where status = 1) and status <> 9 and view_flg = 1 and status <> 3 and ( slkey = :slkey1:) order by slkey desc

Array [3]
file	String/column\cate\lib\classes\AccessRankingList.class - line 39
time	String0.00151800
query	Stringselect t500.*, t510.cname from t515_article_ranking as t515 join t500_article as t500 on (t515.akey = t500.akey) join t510_category as t510 on (t500.ckey = t510.ckey) where t515.date = :date: and t500.ckey != 3 order by t515.pv desc limit 5

Array [3]
file	String/admin\member\channel\lib\classes\ChannelName.class - line 28
time	String0.00165490
query	Stringselect chkey, chname from t200_channel order by sort, chkey

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00154400
query	Stringselect cache_value from t930_cache where cache_name = :cache_name: and chdate >= :chdate:

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00181010
query	Stringselect cache_value from t930_cache where cache_name = :cache_name: and chdate >= :chdate:

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00309680
query	Stringselect cache_value from t930_cache where cache_name = :cache_name: and chdate >= :chdate:

Array [3]
file	StringC:\home\site\wwwroot\module\classes\MYDB.class - line 160
time	String0.00161810
query	Stringselect cache_value from t930_cache where cache_name = :cache_name: and chdate >= :chdate:

Array [3]
file	StringC:\home\site\wwwroot\seminar\lib\classes\SeminarListCore.class - line 139
time	String0.00176500
query	Stringselect * from t300_normal as t300 where t300.status = 1 and chkey in (select chkey from t200_channel where status = 1) and t300.list_view_flg = 1 order by t300.snkey

Array [3]
file	StringC:\home\site\wwwroot\seminar\lib\classes\SeminarListCore.class - line 149
time	String0.00207690
query	Stringselect * from t310_lesson as t310 where t310.status in (1, 2, 3) and ((t310.tdate is null and t310.ldate > :ldate:) or t310.tdate >= :tdate:) order by t310.lkey, t310.ldate, t310.ftime

Array [3]
file	String/seminar\lib\classes\LimitedSeminarList.class - line 44
time	String0.00186900
query	Stringselect * from t430_lesson as t430 join t420_group as t420 on (t430.slkey = t420.slkey and t430.gkey = t420.gkey) where t420.view_flg = 1 and ((t420.tdate is null and t430.ldate > :ldate:) or (t420.tdate >= :tdate: and t430.ldate >= :ldate:)) order by t430.slkey, t430.ldate, t430.ftime

Array [3]
file	String/seminar\lib\classes\LimitedSeminarList.class - line 72
time	String0.00170280
query	Stringselect * from t400_limited where chkey in (select chkey from t200_channel where status = 1) and status <> 9 and view_flg = 1 and status <> 3 and ( slkey = :slkey1:) order by slkey desc

Array [3]
file	String/seminar\lib\classes\LimitedSeminarList.class - line 74
time	String0.00158410
query	Stringselect * from t400_limited where chkey in (select chkey from t200_channel where status = 1) and status <> 9 and view_flg = 1 and status <> 3 and ( slkey = :slkey1:) order by slkey desc

【読込CSS】/C:/home/site/wwwroot/lib/inc/default.tpl - line 63
Null

【読込JS】/C:/home/site/wwwroot/lib/inc/default.tpl - line 63

Array [9]
0	String/js/preset/jquery.js
1	String/js/site.js
2	String/js/preset/form.js
3	String/js/base.js
4	String/js/preset/dump.js
5	String/js/preset/varidate.js
6	String/column/cate/js/note.js
7	String/js/header.js
8	String/js/footer.js

【キャッシュ読み込み】/C:/home/site/wwwroot/lib/inc/default.tpl - line 63

Array [4]
0	String【member】/lib/model/MemberModel
1	String【leave-member】/lib/model/LeaveMemberModel
2	String【article-category】/lib/model/NoteCategoryModel
3	String【channel】/lib/model/ChannelModel

【データ読み込み】/C:/home/site/wwwroot/lib/inc/default.tpl - line 63

Array [1]
0	String/lib/classes/footer/MemberCountController

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